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Case: Nuclear Medicine and PET

A 62-year-old male patient presents with unexplained weight loss and fatigue. A PET scan is ordered to investigate potential causes. The scan reveals areas of increased FDG uptake in the left lung and mediastinum, suggesting possible malignancy. The patient has a history of smoking and chronic obstructive pulmonary disease (COPD).

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What is the most likely diagnosis based on the PET scan findings?